The reigning champions have lost their last two Premier League matches at Old Trafford, 1-0 against both Everton and Newcastle. They bounced back last week with a 3-0 win at Aston Villa but they find themselves 10 points behind table leaders Arsenal. Manchester United have also managed to reach the semi finals of the League Cup after defeating Stoke City but West Ham gained a lot more confidence from that competition as they knocked out Tottenham in the quarter finals earlier this week.
Manchester United are worried about Wayne Rooney's fitness as the England international has a groin injury that kept him out of Wednesday's match at Stoke. Robin van Persie is also out with a thigh injury. "He has got a chance of playing," Moyes said about Rooney on Wednesday. Marouane Fellaini is fit again and could return to action, but fellow midfielder Michael Carrick will surely be out with a calf injury.
Despite the great result in the Capital One Cup, West Ham are struggling in the Premier League, sitting just one point above the relegation zone in 17th position. They have won just one of their last nine league matches and picked up just six points from eight Premier League matches away from home. James Tomkins (groin) could miss out, while strikers Andy Carroll (ankle), Ricardo Vaz Te (shoulder) and Mladen Petric (calf) are still on the sidelines. West Ham have not won at Old Trafford since 2007.
Here are the odds for Saturday's match at Bet365:
Manchester United win - 4/11
Draw - 17/4
West Ham win - 9/1
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